To evaluate the outcome of diagnostic procedures and treatments, a clinical and pathological observation was made on the 162 cases of CIN III(from June 1, 1980 to December 31, 1990) which were confirmed by the Pathological examination of surgical
specimens.
@ES The results were as follows:
@EN The majority were belong to the age gorup of 30~49(75%), married, multiparous and non user of contraception. The mean age was 41 and mean age of marriage was 22.4 About one-fifth were menopaused.
The main presenting symptoms were leukorrehea (37%), lower abdominal discomfort(30.9%), vaginal spotting (22.2%) and post coital spotting(16.7%). About one-fifth were asymptomatic and detected by incidental routine check up.
The most common gross finding was erosion(66.7%) and the others were chronic inflammation with hypertrophy(14.8%), acute inflammation (11.1%). Some cases(5%) disclosed grossly malignant looking, otherwise, the cervix were grossly innocent in 20%.
The cytologic reports were exactly in accord with pathologic of surgical specimens in 63%. The corresponding within one histologic degree was about 87.1%.
The colposcopy showed abnormal finding in 68.7% of the cases. The most common one was white epithelium (57.8%) and the others were punctation(32.8%), mosaicism (17.2%), atypical vessel(10.9%), leukoplakia(1.6%) in order. Those findings were
present
and
mixed together in two third of the cases.
Based upon Pap. Smear, colposcopy with aimed biopsy and conization of the selected cases, the corresponding rate between pre-treatment diagnosis and that of surgical specimen was 98.2%.
The majority (79%) was treated by hysterectomy and the others by conization or local destructive measures.
As to the post treatment complications, the most common one was vaginal vault granulation (28.1%) and the next was cystitis (14.1%). The others were less than 10%, respectively land not problematic.
One case of recurrence was encountered during the mean follow up period of 37 months. Because of insufficient follow up, the status and rate of recurrence are remained to be evaluated by further follow up.
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